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ALFRED: The Allele Frequency Database

Provider: Kenneth K. Kidd, Yale University / US National Science Foundation
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Descriptions: "ALFRED's focus is on allele frequencies in diverse anthropologically defined populations. It is not a compendium of human DNA polymorphisms but of frequencies of selected polymorphisms with an emphasis on those that have been studied in multiple populations. All of the data in ALFRED are considered to be in the public domain and available for use in research and teaching."
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Allen Brain Atlas

Provider: Allen Institute for Brain Science
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Descriptions: "A growing collection of online public resources integrating extensive gene expression and neuroanatomical data, complete with a novel suite of search and viewing tools." Images and gene expression data are available for the mouse brain and spinal cord, and human and non-human primate brains. Excellent video tutorials  provide training in the use of the atlases and the Brain Explorer 2 software.
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CDC Wonder

Provider: CDC (Centers for Disease Control and Prevention)
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Descriptions: CDC WONDER -- Wide-ranging Online Data for Epidemiologic Research -- is a menu-driven system that makes the information resources of the Centers for Disease Control and Prevention (CDC) available to public health professionals and the public. It provides access to a wide array of public health information. Public-use data sets about mortality , cancer incidence, HIV and AIDS, tuberculosis, vaccinations, natality, census data and many other topics are available for query, and the requested data are readily summarized and analyzed in dynamically calculated statistics, charts and maps. The data is compatible with desktop applications such as word processors, spreadsheet programs, or statistical and geographic analysis packages. File formats include plain text (ASCII), web pages (HTML), and spreadsheet files (Tab Separated Values).
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ClinicalTrials.gov

Provider: U.S. National Institutes of Health
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Descriptions: ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world. Currently lists approximately 153,000 studies/trials, with locations in all 50 states and 184 countries.
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DBGET search

Provider: Kyoto University Bioinformatics Center
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Descriptions: DBGET is an integrated database retrieval system for accessing a web of molecular biology databases within GenomeNet and KEGG (Kyoto Encyclopedia of Genes and Genomes.)
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Effective Health Care Program – AHRQ

Provider: Agency for Healthcare Research and Quality (AHRQ)
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Descriptions: First funded by Congress in 2005, the Effective Health Care Program funds and synthesizes the findings of teams of researchers and clinicians across North America, to identify ways to improve the quality of health care through evidence-based decision-making. Research summaries are available for consumers (many with Spanish translations), clinicians and policy-makers. Also for patients, short videos on treatment options, helpful comparative charts on the effectiveness of different treatments for various conditions. Many resources in various formats are provided. The Program invites comments and topic research/review suggestions, and data deposit by medical professionals. Links are provided to plug-ins for viewing video content.
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F1000 Posters

Provider: F1000
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Descriptions: F1000Posters is an open-access repository of posters and slides in biology and medicine. Most are the normally ephemeral products of conference presentations, representing preliminary, unpublished research. F1000 gives this valuable and unique work a permanent home and makes it a resource for all. This provides a mutual benefit for authors and the scientific community, affording an opportunity to share findings and thus further develop ideas and research. More than 5,000 posters have been deposited here as of 2013, in a wide range of biological and medical fields and specialties. Also includes a list of upcoming conferences.
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FedStats

Provider: FedStats.gov
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Descriptions: FedStats is a portal to virtually all the statistics gathered by U.S. Government agencies and bureaus. For some of these, compiling statistics is their main mission; for others, the activity supports their other work. Searches can be done by state or by topic under general subject categories-- agriculture, crime, demographics, education, energy and environment, health, labor, commerce and economics. A full list of agencies is provided, with information on the kinds of statistics they produce. International data of various kinds is also accessible here, some of it comparative.
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FlyBase: A Database of Drosophila Genes and Genomes

Provider: National Institutes of Health
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Descriptions: A visually beautiful, rich and well-organized home for Drosophila researchers, with forums, tools, links to other important sites (including Interactive Fly), high-quality images, a genome browser, and many more helpful tools and features. New FlyBase users can check under the News and link out to the explanatory article, FlyBase 101: the Basics of Navigating FlyBase. The FlyBase project is carried out by a consortium of Drosophila researchers and computer scientists from Harvard University, University of Cambridge, Indiana University and the University of New Mexico, and is funded by grants from NIH, British Medical Research Council, National Science Foundation, and Indiana University
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Global Health Data Exchange (GHDx) – Institute for Health Metrics and Evaluation (IHME)

Provider: Institute for Health Metrics and Evaluation (IHME)
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Descriptions: GHDx is a catalog of the world's health and demographic data. Use the GHDx to research population census data, surveys, registries, indicators and estimates, administrative health data, and financial data related to health. The provider, the IHME, is an educational and research public health organization, and provides fellowships at the bachelor's and graduate levels. IHME publishes the BioMed Central journal, Population Health Metrics, and various open-access reports. There are many interesting resources here. Users should visit the Data Visualizations page and see other items listed under the "Tools" tab.
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Merck Manual Home Health Handbook for Patients and Caregivers

Provider: Merck
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Descriptions: This manual is a valuable medical resource for the layman, explaining medical conditions from every aspect, with introductions giving background information on the biology of body systems and organs, and providing supporting anatomical and 3-D visual aids. Causes, symptoms, diagnosis and treatment are defined. The Drugs section, with information on pharmacokinetics, drug interaction and adverse reactions, herbal supplements and over-the-counter drugs. The Special Subjects area contains information on medical decision-making, limb prosthetics, common imaging tests, travel health, women's health, alternative and complementary medicines, and more.
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NCBI (National Center for Biotechnology Information)

Provider: National Center for Biotechnology Information/National Library of Medicine
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Descriptions: The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. NCBI provides a large number of resources for scientific research, including software and many databases.
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OMMBID (Online Metabolic & Molecular Bases of Inherited Disease)

Provider: McGraw-Hill
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Descriptions: Scriver’s OMMBID,updated several times a year, provides online access to the leading genetic information from renowned international experts. The site now features a researchers' blog, podcasts, the ability to limit searches to images and tables, creation of personal storage and bookmarking.
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PDQ® – NCI’s Comprehensive Cancer Database

Provider: National Cancer Institute
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Descriptions: The PDQ (Physician Data Query) database contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, supportive care, and complementary and alternative medicine; a registry of thousands of open clinical trials from around the world; and directories of physicians, genetic counseling professionals, and organizations that provide cancer care. Also included are a dictionary of cancer terms, statistics on survival, and a drug dictionary.
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PubChem

Provider: National Center for Biotechnology Information/National Library of Medicine
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Descriptions: PubChem provides information on the biological activities of small molecules and is a component of NIH's Molecular Libraries Roadmap Initiative. It includes substance information, compound structures, and bioactivity data in three primary databases: PCSubstance, PCCompound and PCBioAssay. PCSubstance contains more than 12 million records; PCCompound contains more than 7 million unique structures; and PCBioAssay contains more than 200 bioassays.
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Scopus

Provider: Elsevier
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Descriptions: The SCOPUS database contains millions of records from 10,150 life and health sciences publications (including all journals contained in Medline and EmBase) and includes most other sciences and humanities-- coverage of 20,450 journal titles. SCOPUS also indexes the proceedings of 750 conferences.  Searching also pullsl in relevant Web resources, organized under a separate tab. Another tab separates patent results from patent offices in the US and worldwide. SCOPUS provides a Journal Analyzer tool that graphs journals, singly or for comparison, from 1996 to present, showing total citations, number of articles published, total cites divided by number of articles, and the percentage of non-cited articles. Affiliation searching is also provided. A free login for authorized users provides additional advantages: a customizable personal profile for saving citation lists and tracking authors; a publication alert service; and direct export to RefWorks. For SCOPUS's tutorials, click here.  NOTE: Scopus may not support Safari.
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SJR- SCImago Journal and Country Rank

Provider: SCImago
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Descriptions: Based on data indexed in SCOPUS, SJR graphs a number of metrics on scientific publications and publishing. Some unique aspects of the journal analysis include: proportion of cited to uncited/citable to uncitable articles; percentage of a journal's articles that are indicative of research resulting from international collaboration; ranking of countries and regions of the world according to publication output and citation; and an interactive map feature that generates graphic co-citation networks among disciplines, by country and time period. The opening page of SCImago sums it up: "Rank - Analyze - Compare - Visualize."
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Structure (NCBI)

Provider: National Center for Biotechnology Information (NCBI)
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Descriptions: The NCBI Structure Group, a part of the Computational Biology Branch of NCBI, developed this suite of four free molecular and protein databases, each of which is itself made up of several others, and all of which can be searched individually. Macromolecular Structures, Conserved Domains, Small Molecules, and Biological Systems are the four main resources here- tools designed to facilitate discovery of sequence, function and structure associations. The tab labeled "Discover" does a good job of explaining how to use the Structure databases and how to access various facets of information on a molecule or protein from any point in NCBI's many resources.
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WolframAlpha: Computational Knowledge Engine

Provider: Wolfram Alpha, LLC
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Descriptions: WolframAlpha is a computational database/search engine that interprets natural language queries, returning dynamic answers. Although still in development, it currently "...contains 10+ trillion pieces of data, 50,000+ types of algorithms and models, and linguistic capabilities for 1000+ domains." Enter a food item, and the engine generates a page of its nutritional, caloric, vitamin, mineral and physical properties. Input any integer for information about its forms, qualities and expressions. Explore a surname or given name-- view, among other data, its trend in popularity from the 1890's to the present. Input a disease name, and generate a series of graphs illustrating prevalence, average age of onset, sex distribution, medical coverage and more. Use the disease name as a cause of death, and mortality statistics are presented. Apps are now available to download for use with iPhone, iPad and Android.
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