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Showing 1 to 4 of 4 open-source databases. (View all databases)


DrugBank: Open Data Drug & Drug Target Database

Provider: David Wishart/University of Alberta, CA
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Descriptions: A bio- and chemical informatics resource that combines detailed drug (chemical, pharmacological and pharmaceutical) data with comprehensive drug targeting (sequence, structure, and pathway) information. The database contains nearly 4300 drug entries, including FDA-approved small molecule drugs, FDA-approved biotech (protein/peptide) drugs, "nutraceuticals" and experimental drugs. Contains more than 6,800 drug entries with almost 4,300 non-redundant protein sequences linked. Each entry, or  DrugCard, contains more than 80 data fields, half of which are devoted to drug/chemical data and the other half to drug target/protein data. Downloads and information on rights, acknowledgement and usage are available here.
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Gene Ontology

Provider: Gene Ontology Project
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Descriptions: "The Gene Ontology project is a major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases. The project provides a controlled vocabulary of terms for describing gene product characteristics and gene product annotation data from GO Consortium members, as well as tools to access and process this data."  The Ontologies describe three aspects of molecular biology- biological processes, cellular components, and molecular functions. Gene Ontology's collected tools list includes hundreds from all over the world: specialized browsers, search engines, statistical analysis and visualization tools, and many other kinds. This project began as a collaboration between three model organism databases, FlyBase (Drosophila), the Saccharomyces Genome Database  and the Mouse Genome Database  in 1998. Since then, the GO Consortium has grown to include many other databases, including several of the world's major repositories for plant, animal and microbial genomes. See the GO Consortium page for a full list of member organizations.
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Gold Book (IUPAC Compendium of Chemical Terminology)

Provider: IUPAC (International Union of Pure and Applied Chemistry)
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Descriptions: One of a series of Colour Books for chemical nomenclature, terminology, symbols and units. Search the Compendium by text or structure, use an alphabetical index, ring index, math/physics terms index, and more. Interactive graphics (link maps) show how term entries are interrelated and allow navigation through a complex web of connections. References to the literature are included, and are also links. "In the most recent version, the Gold Book is accompanied by a suite of software tools that enable the users to simply add links to the Gold Book to their online materials, especially HTML. These tools are based on tools that are used internally in production of the Gold Book. The software tools are placed separately onSourceForge which allows for easier collaboration on the software."
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NCMIR – National Center for Microscopy and Imaging Research

Provider: National Center for Microscopy and Imaging Research/University of California San Diego
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Descriptions: NCMIR develops technologies to facilitate understanding of biological systems from the gross anatomical to the molecular scale and makes those technologies available to biomedical researchers. NCMIR provides expertise, infrastructure, technological development, and an environment in which new information about the 3D ultrastructure of tissues, cells, and macromolecular complexes can be easily obtained and analyzed.
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