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Showing 1 to 5 of 5 items tagged as bioinformatics


Cold Spring Harbor Protocols

database

Provider: Cold Spring Harbor Laboratory Press
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Descriptions: Cold Spring Harbor Protocols is an interdisciplinary journal providing step by step, peer-reviewed research methods in cell, developmental and molecular biology, genetics, bioinformatics, protein science, computational biology, immunology, neuroscience and imaging. Included is an Alphabetical List of Recipes, listing materials needed for each protocol.
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SpringerProtocols

database

Provider: Springer Science & Business Media LLC
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Descriptions: SpringerProtocols is said to be the most comprehensive and trustworthy online database of reproducible laboratory protocols in the biomedical and life sciences. From the book series Methods in Molecular Biology and numerous other sources, this collection offers researchers access to decades of step-by-step protocols for use in the lab. With an emphasis on clarity, each protocol is organized in an easily-reproduced, recipe style. All protocols have been written by experts in the field, and are reviewed first by editors distinguished in the relevant specific subject areas, and then by Springer's own editorial staff. Contains some open-access protocols. Mobile version of website available.
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GoPubMed

database

Provider: Transinsight
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Descriptions: GoPubMed is an innovative, powerful search tool that combines the MeSH (Medical Subject Headings) and GO (Gene Ontology) terminologies to optimize the effectiveness of queries to PubMed- for everyone, but for molecular biologists in particular. Searching elicits results presented very quickly (maximum display: the most recent 1,000 citations), along with a sidebar presenting the full results in categorized, hierarchical groups of terms that help the user to focus in further- the producers of this search engine refer to it as a "knowledge-based semantic search." There are many more features to this search tool than can be described here.
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Gene Ontology

database

Provider: Gene Ontology Project
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Descriptions: "The Gene Ontology project is a major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases. The project provides a controlled vocabulary of terms for describing gene product characteristics and gene product annotation data from GO Consortium members, as well as tools to access and process this data."  The Ontologies describe three aspects of molecular biology- biological processes, cellular components, and molecular functions. Gene Ontology's collected tools list includes hundreds from all over the world: specialized browsers, search engines, statistical analysis and visualization tools, and many other kinds. This project began as a collaboration between three model organism databases, FlyBase (Drosophila), the Saccharomyces Genome Database  and the Mouse Genome Database  in 1998. Since then, the GO Consortium has grown to include many other databases, including several of the world's major repositories for plant, animal and microbial genomes. See the GO Consortium page for a full list of member organizations.
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DrugBank: Open Data Drug & Drug Target Database

database

Provider: David Wishart/University of Alberta, CA
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Descriptions: A bio- and chemical informatics resource that combines detailed drug (chemical, pharmacological and pharmaceutical) data with comprehensive drug targeting (sequence, structure, and pathway) information. The database contains nearly 4300 drug entries, including FDA-approved small molecule drugs, FDA-approved biotech (protein/peptide) drugs, "nutraceuticals" and experimental drugs. Contains more than 6,800 drug entries with almost 4,300 non-redundant protein sequences linked. Each entry, or  DrugCard, contains more than 80 data fields, half of which are devoted to drug/chemical data and the other half to drug target/protein data. Downloads and information on rights, acknowledgement and usage are available here.
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