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Showing 1 to 72 of 72 items tagged as biomedical research


JoVE (Journal of Visualized Experiments)

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Descriptions: JoVE is a peer-reviewed scientific video journal. It is published in sections, of which the library subscribes to four: Biology, Clinical and Translational Medicine, Immunology and Infection, and Neuroscience. Videos are accompanied by text.
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EMBASE

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Provider: Elsevier
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Descriptions: EMBASE is a comprehensive index to peer-reviewed biomedical literature with international scope, covering 1947-present. EMBASE indexes more than 2,700 journals not covered by PubMed/Medline and includes about 300,000 conference abstracts annually from 2009 to the present. EMBASE combines its own ontology, EMTREE, with that of Medline, so that more of the relevant search results are retrieved in a search. EMBASE is an ideal resource for preparing systematic reviews and tracking drug and medical device information. Supported: IE8, 9 and 10; latest versions of Firefox, Safari and Chrome; Windows XP, Vista and 7, and latest OS X version.
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Structure (NCBI)

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Provider: National Center for Biotechnology Information (NCBI)
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Descriptions: The NCBI Structure Group, a part of the Computational Biology Branch of NCBI, developed this suite of four free molecular and protein databases, each of which is itself made up of several others, and all of which can be searched individually. Macromolecular Structures, Conserved Domains, Small Molecules, and Biological Systems are the four main resources here- tools designed to facilitate discovery of sequence, function and structure associations. The tab labeled "Discover" does a good job of explaining how to use the Structure databases and how to access various facets of information on a molecule or protein from any point in NCBI's many resources.
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Structural Biology Knowledgebase

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Provider: Nature.com and PSI (Protein Structure Initiative)
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Descriptions: The Structural Biology Knowledgebase (SBKB) is the product of a collaboration between the Protein Structure Initiative (PSI) and Nature Publishing Group (NPG.) The site offers an easy way of keeping up to date on the latest developments from the PSI, and more generally, in the fields of structural genomics and structural biology. Some areas of this site require a free registration involving affirmation of a statement declaring that one's purpose is strictly non-commercial and that one is an academic.
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Protein Data Bank: An Information Portal to Biological Macromolecular Structures

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Provider: RCSB (Research Collaboratory for Structural Bioinformatics)
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Descriptions:  "The RCSB (Research Collaboratory for Structural Bioinformatics) is dedicated to improving our understanding of the function of biological systems through the study of the 3-D structure of biological macromolecules. RCSB members work cooperatively and equally through joint grants and subsequently provide free public resources and publications to assist others and further the fields of bioinformatics and biology."  Protein Data Bank (PDB) curates and annotates data according to agreed-upon standards and is a member of the ww (world wide) PDB. Use this database to perform simple and advanced searches based on sequence, structure and function annotations, and to visualize, download, and analyze molecules. The database is primarily for researchers, but the site also includes an entire section (PDB101) of information quite accessible enough for educational purposes. Check out the "Molecule of the Month" feature. The extensive archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies.  As with many scientific databases, a personal log-in affords access to more features. The database is managed by Rutgers and University of California San Diego.
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International Neuroinformatics Coordinating Facility (INCF)

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Provider: International Neuroinformatics Coordinating Facility
Descriptions: INCF develops and maintains database and computational infrastructure for neuroscientists. Software tools and standards for the international neuroinformatics community are developed through INCF programs that address infrastructural issues of high importance to the neuroscience community. INCF collects and makes available neuroinformatics tools in the INCF Software Center, where anyone can upload documentation, executables and related files, track use of their software, create a wiki, and establish development teams. Two of the most popular INCF products are Waxholm Space and MUSIC, which are direct outcomes of the INCF Program on Digital Atlasing and Multi-Scale Modeling, respectively. INCF also arranges Scientific Workshops and holds an annual neuroinformatics conference.
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BioMedSearch.com

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Provider: BioMedSearch.com
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Descriptions: BioMedSearch combines Medline/PubMed citations with data from other sources- dissertations, theses, practice guidelines-  with the aim of creating the most comprehensive biomedical literature search available. Free registration gives the user access to advanced account features: saved searches, alerts, saving documents to portfolios, commentary and sharing of documents with other registered users. Registration is unnecessary for searching without advanced features. This search engine also provides grouped subject clusters and sub-clusters for refinement of results, and detailed syntax instructions and record field abbreviations for use in Advanced search mode. Browser plug-ins are supplied for Chrome, Firefox and Internet Explorer.
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iBridge Network

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Provider: Kauffman Innovation Network, Inc.
Descriptions: "Linking ideas & innovation" is the motto of the iBridge organization. "While traditional search engines provide a means for looking for information, the iBridgeSM Network provides a public, centralized source for unbiased information about early stage technologies and inventions. Our objective is to drive transparency and access to university developed innovations that are available today as well as to field experts, ideas and information. Through the iBridgeSM Network, researchers and those seeking innovations can easily search for and obtain the resources they need." Non-members exploring this site can view the brief descriptions of inventions/innovations by subject or by organization, and see which of these organizations form special communities in iBridge. A free sign-up allows the user to e-mail for more information about the entries. Submissions include technologies that can be licensed, research opportunities, material transfer agreements, and laboratory and equipment availability. The provocative and informative blogs here are accessible to all who visit the site. iBridge is funded in large part by the Kauffman Foundation.
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GenomeNet

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Provider: Kyoto University Bioinformatics Center
Descriptions: GenomeNet is a network of database and computational services for genome research and related research areas in biomedical sciences, operated by the Kyoto University Bioinformatics Center. The service was first developed at Kyoto University as part of a group of research projects begun in 1991 under the Japanese human genome program. It includes bioinformatics tools in sequence, chemical and genome analysis; community databases dealing with cyanobacteria, bacillus subtilis, and gene expression profiles; ontologies; and more. The KEGG database, which has its own entry in this list, is a part of GenomeNet.
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From Birth to Death and Bench to Clinic: The Hastings Center Bioethics Briefing Book

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Provider: The Hastings Center
Descriptions: This online book from the Hastings Center is the collaborative effort of various Hastings Center writers and outside journalists. The Bioethics Briefing Book "seeks to inform debate surrounding thirty-six of the most controversial bioethics topics in the media today." Each chapter begins with an entry highlighting the debated points of the issue, and a comprehensive overview of its various facets follows. Links to information on relevant legislation, 2008 Presidential campaign and party platform positions and links to websites, news items and further reading resources are provided. A few of the topics covered are: gene patents; family-provided long-term care; nanotechnology; abortion; organ transplantation; and stem cells. This book is offered as a free download in .pdf format.
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Flu.gov

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Provider: U.S. Department of Health and Human Services
Descriptions: This DHHS (U.S. Department of Health and Human Services) website presents a wealth of information on the Avian and Swine Influenzas. This is, as the site declares, "one stop access to U.S. Government swine, avian and pandemic flu information." The site provides sections on: planning and preparation, from government to family level; tests, vaccines and medications; bird and animal issues; research activities; global activities; news and multimedia resources; economic impacts; and links to state government websites and contacts.
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Whole Brain Catalog

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Provider: Whole Brain project - UC-San Diego
Descriptions: The Whole Brain Catalog is the flagship project of the Whole Brain Project at the University of California - San Diego. It is an open source, downloadable, multi-scale virtual catalog of the mouse brain and its cellular components, providing zoomable 3D views of structures and their surroundings deep inside the mouse brain. The data is also brought to life with simulation and animation. "In providing open source and collaborative tools, the Whole Brain Project allows neuroscience researchers to make new connections with collaborators and newly discovered data. Combining previously unconnected databases across a single network make possible new and exciting insights about the brain."
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PDQ® – NCI’s Comprehensive Cancer Database

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Provider: National Cancer Institute
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Descriptions: The PDQ (Physician Data Query) database contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, supportive care, and complementary and alternative medicine; a registry of thousands of open clinical trials from around the world; and directories of physicians, genetic counseling professionals, and organizations that provide cancer care. Also included are a dictionary of cancer terms, statistics on survival, and a drug dictionary.
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F1000Research

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Provider: F1000
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Descriptions: F1000Research is an open online journal based on an alternative model of scientific publishing and peer review. Peer review is open, attributed, and done post-publication, once a work has been submitted to internal review and posted. F1000 strongly encourages publication of accompanying datasets under liberal Creative Commons licensing terms. Citations contain information on the stage of refereeing and approval of references. Many Texas Medical Center faculty members are also on the distinguished international editorial staff at F1000.
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F1000 Posters

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Provider: F1000
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Descriptions: F1000Posters is an open-access repository of posters and slides in biology and medicine. Most are the normally ephemeral products of conference presentations, representing preliminary, unpublished research. F1000 gives this valuable and unique work a permanent home and makes it a resource for all. This provides a mutual benefit for authors and the scientific community, affording an opportunity to share findings and thus further develop ideas and research. More than 5,000 posters have been deposited here as of 2013, in a wide range of biological and medical fields and specialties. Also includes a list of upcoming conferences.
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Wiley Online Library

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Provider: John Wiley & Sons, Inc.
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Descriptions: This is the interface for hundreds of Wiley e-journals and e-books, including  Current Protocols . NOTE: The TMC Library subscribes to the Current Protocols in... Immunology; Molecular Biology; NeurologyProtein Science; and Stem Cell Biology.
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DBGET

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Provider: Kyoto University Bioinformatics Center
Descriptions: DBGET is an integrated database retrieval system for accessing a web of molecular biology databases within GenomeNet and KEGG (Kyoto Encyclopedia of Genes and Genomes.)
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DataCite

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Provider: DataCite
Descriptions: DataCite is an international organization established in December, 2009 to promote and facilitate the expansion of the DOI (Digital Object Identifier) system to include scientific datasets. Membership includes publishers, libraries and data centers. Researchers will benefit from access to scientific data supporting findings explicated in full-text articles, and will be able to link to that underlying data in the same way DOI enables links to text. DataCite provides standards and workflows for the publication of this data, and enables researchers to reliably locate and cite submitted data.
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Orphanet: the Portal for Rare Diseases and Orphan Drugs

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Provider: Orphanet and funding organizations
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Descriptions: Orphanet is a portal to regularly-updated information on rare diseases, disorders and syndromes and related "orphan" drug, clinical research and trial, genetic and diagnostic information and includes an encyclopedia and other resources for patients. Orphanet was originally begun and funded in 1997 by the French Ministry of Health and INSERM (Institut National de la Santé et de la Recherche Médicale.) Funding and information-gathering are accomplished and sponsored by various relevant, authoritative European and national organizations.
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OpenThesis

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Provider: OpenThesis.org
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Descriptions: OpenThesis is primarily an international repository of free abstracts of theses, dissertations and other academic documents, enhanced by search, organization and collaboration tools. It also provides e-publishing and conventional publishing services for modest prices, including print-on-demand.
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National Library of Medicine: Databases, Resources and APIs

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Provider: National Library of Medicine
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Descriptions: This is NLM's portal to its approximately 300 research resources, from genetics to the history of medicine, from datasets to mobile apps.  Browse the list with all descriptive information, or search by subject term, type of data or tool, or by terms related to the content or intended audience.
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Catalog of Federal Domestic Assistance

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Provider: U.S. General Services Administration/U.S. Government Printing Office
Descriptions: This is a primary starting point for locating appropriate federal grant funding. This website, in addition to being the primary format of the Catalog, also offers an FAQ and guidance on writing grant applications.
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Cancer Genome Anatomy Project (CGAP)

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Provider: National Cancer Institute
Descriptions: This is a section of the National Cancer Institute website designed specifically for researchers. "The goal of the NCI's Cancer Genome Anatomy Project is to determine the gene expression profiles of normal, precancer, and cancer cells, leading eventually to improved detection, diagnosis, and treatment for the patient. By collaborating with scientists worldwide, CGAP seeks to increase its scientific expertise and expand its databases for the benefit of all cancer researchers. Interconnected modules provide access to all CGAP data, bioinformatics... and biological resources, allowing the user to find "in silico" answers to biological questions in a fraction of the time it once took in the laboratory."
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CAAT: Johns Hopkins University Center for Alternatives to Animal Testing

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Provider: Center for Alternatives to Animal Testing (CAAT)
Descriptions: "We promote humane science by supporting the creation, development, validation, and use of alternatives to animals in research, product safety testing, and education. We seek to effect change by working with scientists in industry, government, and academia to find new ways to replace animals with non-animal methods, reduce the numbers of animals necessary, or refine methods to make them less painful or stressful to the animals involved." The CAAT website also provides educational materials to download, links to related sites, most notably to its own ALTWEB, "the global clearinghouse for information on alternatives to animal testing."
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RePORT Expenditures and Results (RePORTER)

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Provider: National Institutes of Health
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Descriptions: NIH's Research Portfolio Online Reporting Tools (RePORT) facilitates access to information on NIH-funded research activities, including NIH expenditures and the results of NIH-supported research. NIH RePORTER allows users to search a repository of both intra- and extra-mural NIH-funded research projects dating back 25 years, and to access the resulting publications and patents. RePORTER also provides access to data on research funded by other government agencies, including the CDC, the AHRQ, and the Department of Veterans' Affairs.  RePORTER replaced the CRISP database in 2009.
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NIH Data Sharing Repositories

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Provider: National Institutes of Health/National Library of Medicine
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Descriptions: This is a portal with a sortable list of 45 NIH and outside entities' data repositories and data-sharing facilitation sites that offer open-source software. Links to submission and download policies and instructions are provided for each. Research areas include: genomics of the nematode, drosophila, zebrafish and rat; sequencing data; peptides and proteins; pathogens and vectors; the NCI cancer imaging repository; neuroscience, rare diseases, Parkinson's, autism, and more.
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Biomedical Beat: a monthly digest of of research news from NIGMS

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Provider: National Institute of General Medical Sciences/National Institutes of Health
Descriptions: This is a biomedical sciences newsletter on NIGMS-funded research. This National Institutes of Health division funds research in the following areas: cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, bioinformatics and computational biology. Links to sections on research funding opportunities, free publications, and training and other educational grants are made accessible in tabs. In addition, an image library is provided. The newsletter is not copyrighted; articles may be freely reproduced elsewhere; re-use of images requires permissions. This newsletter offers RSS feed access.
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Proteopedia: Life in 3-D

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Provider: Weizmann Institute of Science
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Descriptions: Proteopedia is a free, collaborative (wiki) 3-D encyclopedia of proteins and other molecules. The images can be reduced and restored by component with a toggle, or caused to rotate from any starting angle. Contains an introduction to structural biology and features sections on biomolecules, enzymes, metabolism, gene expression/replication, diseases, immune system, and methods of determining and analyzing structure and sequence. Contains a table of contents and a detailed structure index
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Biographical Memoirs – National Academy of Sciences

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Provider: National Academy of Sciences
Descriptions: This website provides very complete biographical articles on deceased scientists and their work, including extensive bibliographies.
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Neuroscience Information Framework

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Provider: National Institutes of Health
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Descriptions: The Neuroscience Information Framework is a dynamic inventory of web-based neuroscience resources: data, materials, and tools. An initiative of the NIH Blueprint for Neuroscience Research, NIF advances neuroscience research by enabling discovery and access to public research data and tools worldwide through an open source, networked environment. The NIF project is designed to serve the biomedical research community. The more participation from the community, the better the NIF... Collaborating institutions working on the current version of NIF include University of California, San Diego, California Institute of Technology, George Mason University, Yale University Medical College, and Washington University.
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NDB: Nucleic Acid Database

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Provider: The Nucleic Acids Database Research Project/Rutgers University
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Descriptions: A portal for 3-D structural information about nucleic acids, the NDB contains information about experimentally-determined nucleic acids and complex assemblies. Search by annotations relating to sequence, structure and function; download, analyze, and learn about nucleic acids.
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NCMIR – National Center for Microscopy and Imaging Research

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Provider: National Center for Microscopy and Imaging Research/University of California San Diego
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Descriptions: NCMIR develops technologies to facilitate understanding of biological systems from the gross anatomical to the molecular scale and makes those technologies available to biomedical researchers. NCMIR provides expertise, infrastructure, technological development, and an environment in which new information about the 3D ultrastructure of tissues, cells, and macromolecular complexes can be easily obtained and analyzed.
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NCBI Bookshelf

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Provider: National Center for Biotechnology Information
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Descriptions: Collaborating with authors and publishers, the National Center for Biotechnology Information (NCBI) adapts biomedical books for the web. They may either be accessed via direct search or via "Books" links in PubMed abstracts. There are more than 1,400 open-access titles in the Bookshelf. Browse by date, title, subject, publisher and document type. Among the titles are guides to using NCBI databases and sites, Surgeon General reports, and information from various agencies.
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NCBI (National Center for Biotechnology Information)

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Provider: National Center for Biotechnology Information/National Library of Medicine
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Descriptions: The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information. NCBI provides a large number of resources for scientific research, including software and many databases.
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Science.gov

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Provider: usa.gov
Descriptions: Science.gov searches over 36 databases and 1,850 selected websites, offering 200 million pages of authoritative U.S. government science information, including R&D results.
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MeSH (Medical Subject Headings)

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Provider: National Library of Medicine
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Descriptions: MeSH is the National Library of Medicine's controlled vocabulary thesaurus, consisting of sets of descriptors in a hierarchical structure to permit searching with increasing levels of specificity. This thesaurus is used by NLM for indexing articles from the world's leading biomedical journals for the MEDLINE/PubMed® database. It is also used for LocatorPlus, the NLM-produced catalog of books, documents, and audiovisuals acquired by the National Library of Medicine. Each bibliographic record is associated with a set of MeSH terms describing the item's content. MeSH vocabulary can be used in search queries to find items on a desired topic in any NLM database.
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ASBMR Bone Curriculum

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Provider: American Society for Bone and Mineral Research
Descriptions: From the Website: "This is a project of the Education Committee of the American Society for Bone and Mineral Research (ASBMR). It is intended for use by students from high school to medical school. ASBMR's mission is to promote excellence in bone and mineral research, foster integration of clinical and basic sciences and facilitate a translation of our science to health care and clinical practice."
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Quertle

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Provider: Quertle, LLC
Descriptions: Developed by two experts in bioinformatics and data analysis, Quertle offers a uniquely effective way to execute a combined search of the biomedical literature in PubMed, the RePORTER grants database, TOXLINE, and a medical/life science news outlet. This tool also searches the full text of open-access material in BioMed Central and PubMed Central, as well as that of user-submitted scientific whitepapers and research posters. Quertle uses natural-language query constructs very like sentence structure and uses relationships to return relevant results. For details on how it works, see the FAQ tab. A handy brochure on searching and video/other tutorials are found under the Resources tab. Quertle also works with various bibliographic management tools, including RefWorks. Searches can be saved, and alerts service is available (these features require the user to set up a free account.)
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Profiles in Science

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Provider: National Library of Medicine
Descriptions: This collection from the National Library of Medicine provides biographical, career and bibliographic information on a selection of scientists in the medical and biomedical fields.
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PRIM&R: Public Responsibility in Medicine & Research

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Provider: Public Responsibility in Medicine and Research
Descriptions: Via publications and press releases, accreditation, education and networking activities funded through memberships, this organization promotes the ethical treatment of human and animal research subjects. Some of the white papers and general information are freely accessible, but much of the site is restricted to PRIM&R members.
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Office of Rare Diseases Research

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Provider: National Institutes of Health
Descriptions: "The ORDR [Office of Rare Diseases Research] Web site aims to answer questions about rare diseases and the activities of the ORDR for patients, their families, healthcare providers, researchers, educators, students, and anyone with concern for and interest in rare diseases. The site provides information about ORDR-sponsored biomedical research, scientific conferences, and rare and genetic diseases. It also serves as a portal to information on major topics of interest to the rare diseases community."
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KEGG (Kyoto Encyclopedia of Genes and Genomics)

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Provider: Kanehisa Laboratories, Japan
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Descriptions: KEGG is a resource purposed to facilitate understanding of the functions and utilities of the biological system--  cells, organisms and ultimately the ecosystem--  based on genomic and molecular-level information. It is a computer representation of the biological system, consisting of the molecular building blocks-- genes, proteins and chemical substances, integrated with molecular wiring diagrams of interaction, reaction and relational networks. Extensive data is available to view; ftp downloading requires a subscription. KEGG was developed in collaboration with the Bioinformatics Center, Institute for Chemical Research, Kyoto University and the Human Genome Center, Institute of Medical Science, University of Tokyo.
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J-STAGE

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Provider: J-STAGE
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Descriptions: This is a portal to approximately 1,650 open-access journals and 130 proceedings provided by the Japan Science and Technology Agency. Many of the journals are in English; others contain articles in English, or provide English abstracts. Material may be used for personal or academic purposes in accordance with international copyright laws.
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IntegromeDB

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Provider: Researchers at University of California, San Diego
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Descriptions: Created by four university colleagues, IntegromeDB brings together literally hundreds of resources to provide an integrated database of genomic, proteomic, transcriptive, genetic and functional data. Featured in the database are gene function, orthology, gene expression, pathways, protein interactions, mutations and SNPs, disease relationships, and related drugs and compounds. Those not yet familiar with IntegromeDB may want to read the group's open-access article, IntegromeDB: an integrated system and biological search engine.
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NITRC: The Source for Neuroimaging Tools and Resources

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Provider: Neuroimaging Informatics Tools and Resources Clearinghouse
Descriptions: Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) is sponsored by the NIH Blueprint for Neuroscience Research. It offers the neuroscience community free databases and applications for imaging, a forum and a news feed. Researchers can look for applications based on their attributes and popularity, and can also compare similar utilities, check on software development stages, and submit their own databases and applications for sharing. Many links to related resources are also provided here.
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NIH VideoCasting and Podcasting

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Provider: Center for Information Technology, National Institutes of Health
Descriptions: This is a service of the NIH's Center for Information Technology, a growing, searchable collection of National Institutes of Health and Health and Human Services streaming videos and podcasts. Thousands of lectures (including some Grand Rounds), meetings and special events are made available here. Most are open for worldwide public viewing (RealPlayer required.) A minority are restricted to agency employees and clearly marked as such. Lectures and events are also presented live via this site. Reading the FAQ section and testing before playing to an audience is advised. These presentations average about an hour in length and span a wide array of topics.
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NextBio

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Provider: NextBio
Descriptions: NextBio Basic is a free web application providing access to a 'curated, correlated database' of public data which also integrates literature, clinical trials and scientific news. Its semantic framework is based on gene, tissue, disease and compound ontologies. A single search for information on a gene yields results categorically arranged on a single page: an overview of the gene's functions; a list of tissues in which the gene is expressed; diseases and compounds relating to the gene; a list of the top topic-associated researchers and authors; literature, associated clinical trials, and more. Registered users of this application (registration for this basic version is free) can personalize their experience, communicate, collaborate and share data with the rest of the NextBio community.
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Neuroscience Information Framework 3.1

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Provider: National Institutes of Health
Descriptions: The Neuroscience Information Framework (NIF) is a semantically-enhanced portal to a dynamic inventory of Web-based neuroscience resources. An initiative of the NIH Blueprint for Neuroscience Research, NIF enhances discovery and access to often unindexed but publicly available research data, datasets, software and tools in the deep web, as well as linking to PubMed records and open-access literature. The NIF Project provides the NIF Registry, Antibody Registry, Drug Related Gene Database, neuroscience ontology and a way to contribute to it (via the NeuroLex wiki) and semantic tagging services. NIF Navigator, a customizable, stand-alone search tool for incorporation into websites or wikis, draws query results from all the NIF's own components and from other sites and accessible databases. The valuable resources at NIF are too numerous to be described adequately here.
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NBIC (Netherlands BioInformatics Centre)

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Provider: Netherlands BioInformatics Centre
Descriptions: NBIC is engaged in bioinformatics research and education. Its website includes free software downloads, information on databases and projects, a journal and newsletter, and secondary-level education materials.
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Nature Network

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Provider: Nature Publishing Group
Descriptions: Hosted by Nature Publishing Group, Nature Network is a collection of very active blogs and forums where scientists network and discuss science and research, concretely or philosophically. As the website's header says, "Connect - Discuss - Explore - Search." Disciplines represented: neuroscience, genetics, bioinformatics, physics, chemistry, virology, proteomics, and many more.
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National Science Foundation

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Provider: National Science Foundation
Descriptions: The National Science Foundation (NSF) offers full grant-funding information to the research community- from opportunity, to application deadline, to awards. NSF policy on data sharing and data management are also provided here. Those seeking grant information may want to go straight to the Site Map for faster navigation to their areas of interest. The NSF funds approximately 10,000 new scientific grant awards annually for research in a variety of scientific fields. To the general public, the NSF site provides a multimedia gallery of news, speeches and lectures, special reports and overviews of NSF research.
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National Institute on Aging

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Provider: U.S. National Institutes of Health
Descriptions: "NIA, one of the 27 Institutes and Centers of NIH, leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. In 1974, Congress granted authority to form NIA to provide leadership in aging research, training, health information dissemination, and other programs relevant to aging and older people. Subsequent amendments to this legislation designated the NIA as the primary Federal agency on Alzheimer’s disease research." A large number of free publications, some provided in Spanish, are available for downloading. These include fact sheets, reports and a short e-book, Alzheimer's Disease: Unraveling the Mystery. Links to information about research projects, trials, health- and aging-related organizations, and other related resources are provided.
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National Institute of General Medical Sciences (NIGMS)

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Provider: NIGMS - National Institute of General Medical Sciences
Descriptions: "The mission of [NIGMS] is to support research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment, and prevention." NIGMS provides training and career grants, including a grants and opportunities program for minorities. This website is a gold mine for educators, providing scientist interviews, short films on special topics, an image database, posters, fact sheets, even interactive games. One can access or sign up for Biomedical Beat, the free NIGMS online newsletter, as well as order many other free publications. For researchers there is a blog, NIGMS Feedback Loop, that keeps one up to date on funding opportunities and future plans.
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National Heart, Lung and Blood Institute (NHLBI)

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Provider: National Institutes of Health
Descriptions: "The Institute plans, conducts, fosters and supports an integrated and coordinated program of basic research, clinical investigations and trials, observational studies, and demonstration and education projects." There is a wealth of information here, through links and integral content, for patients, researchers and health care professionals. Includes information on new clinical trials and provides links to individual clinical trial websites. For consumers, there is a special Health Information Network one can sign up for, which will then feed only the information of particular interest to the individual user.
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GoPubMed

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Provider: Transinsight
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Descriptions: GoPubMed is an innovative, powerful search tool that combines the MeSH (Medical Subject Headings) and GO (Gene Ontology) terminologies to optimize the effectiveness of queries to PubMed- for everyone, but for molecular biologists in particular. Searching elicits results presented very quickly (maximum display: the most recent 1,000 citations), along with a sidebar presenting the full results in categorized, hierarchical groups of terms that help the user to focus in further- the producers of this search engine refer to it as a "knowledge-based semantic search." There are many more features to this search tool than can be described here.
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GigaDB

database

Provider: GigaScience and BGI
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Descriptions: GigaDB is an open repository of datasets that support the research published in the open access BioMed Central bioinformatics journal, GigaScience. GigaDB provides a place from which to download supporting data and tools associated with papers published in GigaScience, thus facilitating the reproducibility of research. DataCite DOIs are assigned to these accompanying datasets, an identification device which serves to facilitate tracking and discoverability, and to provide additional credit to the authors who make their data publicly available.
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Frontiers

database

Provider: Frontiers
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Descriptions: Frontiers was launched in 2007 by scientists from the Swiss Federal Institute of  Technology in a grassroots initiative.  Frontiers is an open-access, scholarly, primarily scientific publisher, producing 26 community-driven journals with growing impact factors, and with more than 25,000 high-impact researchers on its editorial boards. Frontiers is notable for a democratic system of peer review, the details of which can be examined under the "About" section. Authors with accepted articles who demonstrably cannot bear the cost of publication can apply to the Frontiers Research Foundation for a grant to waive some or all author fees. Waivers are dependent on the World Bank economic status of the author's country. Many video lectures are posted in a keyword-searchable, subject-browse interface. Read abstracts of about 180 downloadable e-books, which can be purchased for a negligible fee. The Frontiers Community part of the site is home to an image bank, an international conference/events schedule, a blogging platform with numerous active blogs, and a jobs board. Authors, editors and reviewers come from prestigious institutions worldwide, many of them from the Texas Medical Center. To participate in the networking components, Frontiers Research Network and Frontiers Community, complete the free online registration form. Maintain contact and receive alerts via almost any social networking tool or via RSS feed. Many TMC researchers participate.
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NanoHub.org

website

Provider: Network for Computational Nanotechnology
Descriptions: Supported by the National Science Foundation, this site is designed for and by the nanotech research community, providing tools and support for nanotech theory, modeling and simulation, and a forum in which to share knowledge within and between different nanotech research areas. This site is also a good resource for teachers, supplying curriculum items in the form of images, videos and learning modules.
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MayoClinic.com

website

Provider: Mayo Foundation for Medical Education and Research
Descriptions: The Mayo Clinic website's mission is, in part, to empower people to manage their own health. To that end, it provides consumers with a diseases and conditions/symptom information section, a drugs and supplements section, information on clinical trials by category. For the medical professional there are open-access Grand Rounds videos and continuing education opportunities. For all, there is Discovery's Edge, an online open-access magazine that highlights Mayo Clinic's research activities in layman's terms.
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Lister Hill National Center for Biomedical Communications

website

Provider: National Library of Medicine
Descriptions: A research and development division of the U.S. National Library of Medicine, the Lister Hill Center conducts and supports research and development in the dissemination of high quality imagery, medical language processing, high-speed access to biomedical information, intelligent database systems development, multimedia visualization, knowledge management, data mining and machine-assisted indexing. A diverse staff with backgrounds in medicine, computer science, library and information sciences, linguistics, cognitive science, education, and engineering are committed to maintaining the Lister Hill Center's leadership position in biomedical information research and development.
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DBGET search

database

Provider: Kyoto University Bioinformatics Center
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Descriptions: DBGET is an integrated database retrieval system for accessing a web of molecular biology databases within GenomeNet and KEGG (Kyoto Encyclopedia of Genes and Genomes.)
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Cell, the: An Image Libary

database

Provider: American Society for Cell Biology
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Descriptions: Supported by an award from National Institute of General Medical Sciences (NIGMS) and NIH, this is a peer-reviewed repository of thousands of often stunning microscopic images of cell types, processes and components. Most are free to use or under Creative Commons license by the authors, rather than restricted by publisher copyright. Free sign-in gives the user the ability to save images in a folder. Broader features like multiple public and private folders, sharing and annotation are in development. Many videos are also posted. Researchers are urged to contribute from their own work and experiments. For more information on the intent and the many current as well as future features of the database, read more at Leica Science Lab.
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BIOSIS – Biological Abstracts, 1980 – 2003

database

Provider: Ovid
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Descriptions: BIOSIS encompasses the breadth of life sciences and provides coverage of published biological and biomedical research; includes traditional areas of biology, such as botany, zoology and microbiology, as well as experimental, clinical and veterinary medicine, biotechnology, environmental studies, and agriculture. Interdisciplinary fields like biochemistry, biophysics and bioengineering are also included. The Library's coverage ends with 2003. For a brief guide to searching any Ovid database, access the full list of available databases by clicking "Change Databases," and click the "i" (information) logo next to its title.
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BioMed Central

database

Provider: BioMed Central
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Descriptions: BioMed Central is a Science, Technology and Medicine (STM) publisher of more than 250 peer-reviewed open access journals. The journals here cover many specialty areas of biology, biomedicine and medicine and include broad interest titles as well.  All original research articles published by BioMed Central are freely accessible online upon publication. Other content in a minority of the journals is subscription-based. Articles labelled Open Access are immediately and permanently available online. Unrestricted use, distribution and reproduction in any medium is permitted, provided the article is properly cited. See BioMed Central's open access charter. Search BioMed Central by journal, or browse by article.
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BioMart Bio Portal

database

Provider: BioMart
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Descriptions: The BioMart project provides free software and data services to the international scientific community in order to foster scientific collaboration and facilitate the scientific discovery process. The project adheres to the open source philosophy of promoting collaboration and code reuse. The majority of the contributed databases are of plant or human genomics-oriented data. Under Community, view the linked database list with descriptions and contributor names. Databases originate from the UK, USA, France, Spain, China and other countries. There are three separate portal websites-- the central "Bio" portal, a cancer portal, and one for mouse data.  Unfortunately, no link back to BioMart is provided once the user accesses one of the other portals.
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Biology Image Library

database

Provider: BioMed Central
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Descriptions: The Biology Image Library allows free access to view image thumbnails and annotations, but only a subscription (which The TMC Library does not provide) enables  the viewing and use of full-sized images not in the public domain. The scientific community is invited to contribute images of significance and high visual quality that are accompanied by descriptive annotation. Certain benefits apply- check under About thAdd Newe Library/How to Contribute.
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DrugBank: Open Data Drug & Drug Target Database

database

Provider: David Wishart/University of Alberta, CA
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Descriptions: A bio- and chemical informatics resource that combines detailed drug (chemical, pharmacological and pharmaceutical) data with comprehensive drug targeting (sequence, structure, and pathway) information. The database contains nearly 4300 drug entries, including FDA-approved small molecule drugs, FDA-approved biotech (protein/peptide) drugs, "nutraceuticals" and experimental drugs. Contains more than 6,800 drug entries with almost 4,300 non-redundant protein sequences linked. Each entry, or  DrugCard, contains more than 80 data fields, half of which are devoted to drug/chemical data and the other half to drug target/protein data. Downloads and information on rights, acknowledgement and usage are available here.
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Alzforum (Alzheimer Research Forum)

website

Provider: Alzheimer Research Forum
Descriptions: This site contains and links to a huge number of resources for the Alzheimer researcher. Features include: a live discussion forum; citations to the latest papers (linking to PubMed); an international listing of institutes and laboratories; separate links for news on drugs, conferences and research; clinics information for the consumer; and more items too numerous to list here. It also provides links to the AlzSWAN Knowledge Base (see separate website listing) and its tutorials, and a collection of special seminars, on-line journal club discussions, recorded talks and other presentations that describe a variety of scientific hypotheses about the pathogenesis of Alzheimer's disease.
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PubMed

database

Provider: National Library of Medicine
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Descriptions: PubMed is a bibliographic database providing abstracts to articles in medicine, nursing, dentistry, veterinary medicine, allied health, and the pre-clinical sciences; it is the Index Medicus and provides access to articles in the Index to Dental Literature and the International Nursing Index. PubMed is a service of the US National Library of Medicine. Includes millions of citations from health and life sciences journals from the present back to the 1950s. PubMed, when accessed by registered Academic users via a TMC Library link, brings the user full text of thousands of articles in subscribed journals. For all who access it, PubMed also links to thousands of open-access articles, either directly via publisher sites or via its PubMed Central repository.
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Current Protocols

database

Provider: John Wiley & Sons
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Descriptions: Users have access to the following laboratory protocols via the TMC Library:


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Scopus

database

Provider: Elsevier
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Descriptions: The SCOPUS database contains millions of records from 10,150 life and health sciences publications (including all journals contained in Medline and EmBase) and includes most other sciences and humanities-- coverage of 20,450 journal titles. SCOPUS also indexes the proceedings of 750 conferences.  Searching also pullsl in relevant Web resources, organized under a separate tab. Another tab separates patent results from patent offices in the US and worldwide. SCOPUS provides a Journal Analyzer tool that graphs journals, singly or for comparison, from 1996 to present, showing total citations, number of articles published, total cites divided by number of articles, and the percentage of non-cited articles. Affiliation searching is also provided. A free login for authorized users provides additional advantages: a customizable personal profile for saving citation lists and tracking authors; a publication alert service; and direct export to RefWorks. For SCOPUS's tutorials, click here.  NOTE: Scopus may not support Safari and will cease to support IE7 in September 2014. From the website: "In order for our users to continue benefitting from Scopus’ new features and functionalities, we recommend that you upgrade your browser to IE 8 or higher or use Google Chrome or Firefox browsers."
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1000 Genomes

database

Provider: 1000 Genomes
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Descriptions: 1000 Genomes: a deep catalog of human genetic variation "...is the first project to sequence the genomes of a large number of people, to provide a comprehensive resource on human genetic variation... The goal of the 1000 Genomes Project is to find most genetic variants that have frequencies of at least 1% in the populations studied." 1000 Genomes is an international endeavor, with participants from institutes, governments and universities world-wide. "DNA from the samples will be available for researchers to follow up with more detailed studies of variation in particular regions. The cell lines will allow researches to study cellular phenotypes such as gene expression, epigenetic patterns, and drug response. The extensive genotype data available on the samples, and the trio samples for some of the populations, will allow researchers to map regions of the genome computationally that affect the cellular phenotypes, and to study the heritability of these phenotypes."
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