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Showing 1 to 7 of 7 items tagged as mutations


Structure (NCBI)

database

Provider: National Center for Biotechnology Information (NCBI)
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Descriptions: The NCBI Structure Group, a part of the Computational Biology Branch of NCBI, developed this suite of four free molecular and protein databases, each of which is itself made up of several others, and all of which can be searched individually. Macromolecular Structures, Conserved Domains, Small Molecules, and Biological Systems are the four main resources here- tools designed to facilitate discovery of sequence, function and structure associations. The tab labeled "Discover" does a good job of explaining how to use the Structure databases and how to access various facets of information on a molecule or protein from any point in NCBI's many resources.
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Proteopedia: Life in 3-D

database

Provider: Weizmann Institute of Science
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Descriptions: Proteopedia is a free, collaborative (wiki) 3-D encyclopedia of proteins and other molecules. The images can be reduced and restored by component with a toggle, or caused to rotate from any starting angle. Contains an introduction to structural biology and features sections on biomolecules, enzymes, metabolism, gene expression/replication, diseases, immune system, and methods of determining and analyzing structure and sequence. Contains a table of contents and a detailed structure index
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Genetics Home Reference: Your Guide to Understanding Genetic Conditions

database

Provider: National Library of Medicine
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Descriptions: This is the National Library of Medicine's web site for consumer information about genetic conditions. Includes condition, gene, and chromosome summaries, the Help Me Understand Genetics Handbook (with basic explanations of how genes work, genetic testing, and the Human Genome Project) and a glossary of genetic and medical terms.
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Interactive Fly

database

Provider: Society for Developmental Biology
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Descriptions: "A cyberspace guide to Drosophila development and metazoan evolution." This database won a Scientific American Sci-Tech Web Award (2002) and has also been featured in the Internet Scout Report. Sections: Biochemical Pathways, Organs, cis-Decoder, Labs and References, and more. Includes a gene index with extensive information on each gene, and a section on tissue and organ development.
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FlyBase: A Database of Drosophila Genes and Genomes

database

Provider: National Institutes of Health
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Descriptions: A visually beautiful, rich and well-organized home for Drosophila researchers, with forums, tools, links to other important sites (including Interactive Fly), high-quality images, a genome browser, and many more helpful tools and features. New FlyBase users can check under the News and link out to the explanatory article, FlyBase 101: the Basics of Navigating FlyBase. The FlyBase project is carried out by a consortium of Drosophila researchers and computer scientists from Harvard University, University of Cambridge, Indiana University and the University of New Mexico, and is funded by grants from NIH, British Medical Research Council, National Science Foundation, and Indiana University
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BioMart Bio Portal

database

Provider: BioMart
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Descriptions: The BioMart project provides free software and data services to the international scientific community in order to foster scientific collaboration and facilitate the scientific discovery process. The project adheres to the open source philosophy of promoting collaboration and code reuse. The majority of the contributed databases are of plant or human genomics-oriented data. Under Community, view the linked database list with descriptions and contributor names. Databases originate from the UK, USA, France, Spain, China and other countries. There are three separate portal websites-- the central "Bio" portal, a cancer portal, and one for mouse data.  Unfortunately, no link back to BioMart is provided once the user accesses one of the other portals.
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1000 Genomes

database

Provider: 1000 Genomes
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Access Level:
Descriptions: 1000 Genomes: a deep catalog of human genetic variation "...is the first project to sequence the genomes of a large number of people, to provide a comprehensive resource on human genetic variation... The goal of the 1000 Genomes Project is to find most genetic variants that have frequencies of at least 1% in the populations studied." 1000 Genomes is an international endeavor, with participants from institutes, governments and universities world-wide. "DNA from the samples will be available for researchers to follow up with more detailed studies of variation in particular regions. The cell lines will allow researches to study cellular phenotypes such as gene expression, epigenetic patterns, and drug response. The extensive genotype data available on the samples, and the trio samples for some of the populations, will allow researchers to map regions of the genome computationally that affect the cellular phenotypes, and to study the heritability of these phenotypes."
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